Vezilić was born in a Serbian village called Stari Ker, today's Zmajevo, situated in the Vrbas municipality, in the South Bačka District, Vojvodina province, then part of the Austrian Military Frontier, on 17 July 1753.
[1] He completed his early schooling in Novi Sad and Segedin, and studied Latin and German at the universities of Buda and Pest.
In 1790 he was offered the post of regent of Serbian and Romanian Orthodox schools in what was then called the Velikovardar and Eger districts in Hungary.
He belongs to the race of poetical reformers who appeared in all countries of Europe at the end of the eighteenth century; but it is interesting to observe that in point of time he preceded all of them.
Vezilić was the founder of classicism in Serbian literature, but it was the work of Lukijan Mušicki which, according to Jovan Skerlić, brought it to its apogee.