[3][4] During the First World War Biroli fought in the Macedonian Front as commander of one battalion of Italian Army who was decorated by the Government of the Kingdom of Serbia with the Order of the White Eagle with swords.

He commanded the Eritrean Corps in the Second Italo-Abyssinian War, and subsequently was Governor of Amhara province in Italian East Africa from 1936 to 1937.

[12] As early as 1941, Pirzio Biroli considered creating of an collaborationist committee, which would gather all notable collaborators in Montenegro against Yugoslav Partisans.

Because of opposition from Italian Ministry of Foreign Affairs, creation was delayed until July 24, 1942 when former Ban of Zeta Banovina Blažo Đukanović signed a deal with Pirzio Biroli to head Central Nationalist Committee.

[14] According to Yugoslav historian Pajović, Pirzio Biroli was personally responsible for numerous executions and mass terror of the population of Montenegro.