Alessio Simmaco Mazzocchi (21 October 1684 – 12 September 1771) was an Italian priest, antiquary and philologist.

[1] In 1711 he was made a canon of the Cathedral of Capua and in 1735 he was appointed professor of theology and Sacred Scripture at the University of Naples.

[4] Mazzocchi was a friend of Francesco Scipione Maffei, Jacopo Facciolati and Ludovico Antonio Muratori.

[2] He was a member of several learned societies, including the Accademia Ercolanese and the Académie des Inscriptions et Belles-Lettres.

He published also an improved edition of Vossius' Etymologicon linguae Latinae (Naples, 1762) and dissertations on Hebrew poetry and on the Antiquities of the Roman Campagna.