[11] Chalk prosecuted serious fraud cases, including a case against the socialite Edward Davenport, known as Fast Eddie, who was convicted in 2011 of being the ringmaster of a global fraud which saw 51 victims, including Elizabeth Emanuel, the dress designer, pay for "due diligence checks" to secure loans totalling £2 billion which were not genuinely on offer.

[12] He also prosecuted rape and sexual assault cases, including against five men who lured two girls to a house and subjected them to a weekend of sex attacks; they were convicted.

[13] He has also advised and defended corporate clients, and prosecuted for HM Revenue and Customs and the Department of Business, Innovation and Skills.

[15] Chalk was first elected as a Conservative councillor for Shepherds Bush Green ward on Hammersmith and Fulham Council in May 2006.

[23] Following a lengthy investigation, the Crown Prosecution Service said it would take no further action against any Conservative candidates or party official, including Alex Chalk.

He supported the government by voting to trigger Article 50, which formally began the process of Britain's exit from the European Union, along with a majority of cross-party MPs,[40] as a way of respecting the referendum result.

[42] In May 2017, the Crown Prosecution Service concluded its investigations into the allegations and determined that no Conservative Party candidates or officials would face charges.

"[44] Chalk was re-elected as MP for Cheltenham at the snap 2017 general election with an increased vote share of 46.7% and a decreased majority of 2,569.

[52] Chalk advocated a "moderate, compromise deal" with cross-party colleagues,[53] but since 2019 consistently voted in Parliament to support government legislation to leave the EU.

[54] On 10 September 2019 at an impromptu meeting with Cheltenham residents in Pittville Park, called to talk about the controversial prorogation of Parliament, Chalk stated[55] "If there is a scintilla of a suggestion that the British government would act unlawfully, forget it, game over.

[57] In March 2021, Chalk announced measures to protect young people who fall victim to sexual predators working as sports coaches and faith leaders.

Alongside his Ministerial colleagues at the Ministry of Justice, Chalk tabled new laws in the Police, Crime, Sentencing and Courts Bill to prohibit those in a position of trust from engaging in sexual activity with a child in their care.

[59] In May 2021, it was reported by The Times that Chalk had told prison officials that they "must stop calling inmates residents, clients or supervised individuals because it creates the wrong impression of criminals".

[61] Chalk also announced that charities and companies which help rehabilitate offenders had been awarded around £200 million of Government funding to provide support services that help reduce reoffending, such as employment and housing advice.

[65] In August 2021, Chalk announced that thousands more solar panels will be fitted to prisons to help cut carbon emissions and to save taxpayers' money.

[68] As Solicitor General, Chalk sought to ensure that criminals receive custodial sentences that appropriately reflect the nature of their crimes.

These offenders include Milad Rouf,[69] who threw acid in the face of a former partner, and Christopher Appleby,[70] who sexually abused three girls over a period of 15 years.

[71] Ben John, aged 22, was in possession of tens of thousands of politically extreme and far-right documents and files, including white nationalist and anti-Semitic materials.

[80] On 24 August 2023, Chalk ordered an inquiry into the wrongful conviction of Andrew Malkinson, stating that he "suffered an atrocious miscarriage of justice and he deserves thorough and honest answers as to how and why it took so long to uncover".