Alexander Manuel Colomé Pérez (born December 31, 1988) is a Dominican professional baseball pitcher who is a free agent.

He has previously played in Major League Baseball (MLB) for the Tampa Bay Rays, Seattle Mariners, Minnesota Twins, Colorado Rockies, and Chicago White Sox.

At age eighteen, Colomé signed with the Tampa Bay Devil Rays as an amateur free agent in March 2007.

[citation needed] In 2016, Colomé was named the full-time closer for the Rays due to an injury to Brad Boxberger.

[6] On May 25, 2018, the Rays traded Colomé and outfielder Denard Span to the Seattle Mariners in exchange for minor leaguers Andrew Moore and Tommy Romero.

[8] He made 62 relief outings for Chicago in 2019, registering a 4-5 record and 2.80 ERA with 55 strikeouts and 30 saves across 61 innings pitched.

[9] With the 2020 Chicago White Sox, Colomé appeared in 21 games, compiling a 2–0 record with 0.81 ERA and 16 strikeouts in 22+1⁄3 innings pitched.