[1] He received his secondary education in Ghana at Mfantsipim School at Cape Coast in the Central Region and studied at the Intermediate Department at Achimota College near Accra.

He then went to the United Kingdom, where he studied Philosophy, Politics and Economics at Exeter College, Oxford University, graduating with an honours degree.

He was on a trip to North Vietnam with Nkrumah when the government was overthrown by a military coup d'état leading to the formation of the National Liberation Council on 24 February 1966 led by Lt. General Joseph Arthur Ankrah.

[1] Quaison-Sackey died aged 68 at Korle Bu Teaching Hospital in Accra, following a pulmonary embolism on 21 December 1992.

Quaison-Sackey later wrote about his experiences of diplomatic issues in Ghana's early days in a book called Africa Unbound: Reflections of an African Statesman, which was published by Praeger in May 1963.