He originally wanted to be a journalist, but applied and failed the entrance exam to the Danish Media and Journalism School in Aarhus after taking the wrong bus.

[6] The election was catastrophic for the Liberal Alliance, which lost nine of thirteen seats and its leader Anders Samuelsen failing to be reelected.

[7][8][9] Vanopslagh has been a prominent critic of Prime Minister Mette Frederiksen and her government, due to alleged attacks on fundamental institutions, rights and common sense.

[10] He has referred to Frederiksen as "the worst news for our democracy and justice state since World War II".

[14] Under Vanopslagh, the Liberal Alliance has seen a major rise in popularity, especially during campaigning for the 2022 Danish general election.