By 1650, Spaen served as a Landdrost, a government councillor, and an Oberst (colonel), and he became the leader of a cavalry regiment the following year.
In 1654 he captured Dietrich Karl zu Wylich-Winnenthal, the leader of an uprising against Elector Frederick William, and brought him to Spandau.
Spaen led Prussia's Horse Guards (Leibregiment zu Pferde) during the Northern Wars, participating in the Battle of Warsaw.
During the War of the Grand Alliance against France, Spaen participated in the siege of Bonn and the Battle of Fleurus.
Before the August 1919 abolition of nobility as a legal class, titles preceded the full name when given (Graf Helmuth James von Moltke).