[2][3] She attended the New York University Tisch School of the Arts where she studied at the affiliated Stella Adler Conservatory,[4] graduating with honors with a double degree in Drama and Psychology.

[4][5] Lydon co-created and performed in the comedy show Worst Laid Plans at the Upright Citizens Brigade Theatre[4] in Los Angeles and New York City.

She wrote and performed in the comedy album Worst Laid Plans at the Upright Citizens Brigade Theatre, published by Random House in May 2010.

[6] She later adapted the show into a book, Worst Laid Plans: When Bad Sex Happens to Good People, published in 2014 by Abrams Image.

[8] Inspired by the first female policewomen in Boston, Lydon created and produced the 2015 ABC TV movie Broad Squad.