Alexandre Rocha Santos Padilha is a Brazilian physician and politician affiliated with the Workers Party (PT).

[1] He serves as minister of Institutional Relations in the current government of President Luiz Inácio Lula da Silva, a position he previously held from 2009 to 2011.

He served as minister of health under Dilma Rousseff from 2011 to 2014.

[2] He unsuccessfully ran for governor of São Paulo state in the 2014 election.

[3] On 1 January 2023, he was once again named Secretary of Institutional Affairs by President Luiz Inácio Lula da Silva, who reinstated the office.