Alexios Komnenos Strategopoulos (Greek: Ἀλέξιος Κομνηνὸς Στρατηγόπουλος) was a Byzantine aristocrat and general who rose to the rank of megas domestikos and Caesar.

[8] Alexios Strategopoulos first appears in the chronicles in 1252–53, during the reign of John III Doukas Vatatzes, when he led a detachment of the army sent to plunder the areas of Nicaea's Greek rival, the Despotate of Epirus, around Lake Ostrovo.

[6][9] In 1254, he was based at Serres in Macedonia, and in the next year he participated, along with megas primmikerios Constantine Tornikes, in a campaign against the fortress of Tzepaina in the western Rhodope Mountains.

The contemporary historian George Akropolites puts the blame on the bad generalship shown by the two commanders, who failed to reconnoitre properly the Bulgarian forces opposing them.

[6][13] In 1259 he participated in the campaign that led to the decisive victory over an Epirote–Sicilian–Achaean alliance at the Battle of Pelagonia, where, along with Nikephoros Rimpsas, he took captive the 400-strong detachment of German knights sent by King Manfred of Sicily to aid the Epirotes.

Strategopoulos and Petraliphas crossed the Pindus Mountains, bypassed Ioannina, which they left under siege, and captured the Epirote capital, Arta, forcing the Despot Michael II to flee to the island of Cephalonia.

[12][16][17] In the next year, however, the Nicaean successes were largely undone: Despot Michael with his sons and an Italian mercenary army landed at Arta, and the Epirote population rallied to his cause.

[20] Strategopoulos initially hesitated to take advantage of the situation, since his small force might be destroyed if the Latin army returned too soon, and because he would exceed the emperor's orders, but eventually decided he could not squander such a golden opportunity to retake the city.

As news of this spread across the city, the Latin inhabitants, from Emperor Baldwin II downwards, hurriedly rushed to the harbours of the Golden Horn, hoping to escape by ship.

[22] The recapture of Constantinople signalled the restoration of the Byzantine Empire, and on 15 August, the day of the Dormition of the Theotokos, Emperor Michael VIII entered the city in triumph and was crowned at the Hagia Sophia.