Alexis is an unincorporated community in Cherokee County, in the U.S. state of Alabama.

A post office called Alexis was established in 1884, and remained in operation until it was discontinued in 1906.

[2] Alexis is the Anglicization of a Cherokee name, according to local history.

[3] According to the returns from 1850[4]-2010[5] for Alabama, Alexis has never reported a population figure separately on the U.S.

This Cherokee County, Alabama state location article is a stub.