[3] Born in 1979, Alexis Mateo began her drag career in Puerto Rico's gay nightclub circuit before relocating in 2001 to Orlando, Florida, where she worked as a dancer and performer at Disney World.

After being featured in a Gilead Sciences ad titled "Red Ribbon Runway" with fellow Drag Race co-stars Manila Luzon, Delta Work, Shangela Laquifa Wadley, and Carmen Carrera,[9] the dress he was featured wearing was auctioned off by Logo in commemoration of World AIDS Day.

Mateo joined as a cast member on the third season of Logo's reality series, RuPaul's Drag Race, which premiered on the network on January 29, 2011.

Mateo won three of the main challenges (Episodes 2, 3, and 8) before making it to the top three, where he was eliminated in the season finale which aired on April 25, 2011.

[19] Mateo resides in Las Vegas, Nevada, where he performs at gay venues and events both locally and throughout the United States.

In April 2011, Mateo along with fellow contestant Yara Sofia launched a boycott of a Tampa beauty supply shop after the two claimed they had been told to leave the store because of their sexual orientation.