He initially gained prominence working for O Heraldo during the height of the Konkani language agitation and Goa's statehood struggle in the 1980s.

[6] Alexyz's upbringing in Bombay exposed him to tiatr (Goan musical theatre), as his uncle often entertained guests with renditions of popular Konkani songs by tiatrist Kid Boxer.

Miranda started working on cartoons shortly after completing his education, contrasting Alexyz, who took a more extended period, around eight years post-graduation, to discover his own potential.

Miranda also introduced Alexyz and Erasmo de Sequeira, who was responsible for the operations of the Goan newspaper, Goa Monitor.

He was recognised for his cartoons published in O Heraldo, which provided him with extensive creative freedom and space to contribute to the ongoing Konkani language agitation and Goa's statehood struggle.

This allowed him to frequently comment on the political events and issues central to the regional autonomy and linguistic rights campaigns, through his distinctive visual style.

[5] In 2000, Alexyz was invited by British Member of Parliament, Keith Vaz, to organise a three-day exhibition of his cartoons at the House of Commons in London.

In 2015, he authored a book, O To Be In Goa... Today, dedicating it to three of his close associates: fellow cartoonist Mario Miranda, musician Emiliano da Cruz, and journalist-photographer Joel D'Souza.

Over the course of his career, Alexyz had amassed a substantial portfolio of thousands of cartoons, including his initial published piece in a parish magazine located in Wadala.

In addition to his autobiography, Alexyz made artistic contributions to an updated version of Greatest Konkani Songs Volume 2, authored by Francis Rodrigues, who is based in Canada.

Despite the financial challenges often associated with a career in cartooning, Alexyz remained actively engaged in sharing his artistic talents.