The family returned to Puerto Rico and in 1910, his father, Ramón Valdés founded and organized the "Mayaguez Light, Power and Ice Company", a utility in the city of Mayagüez.

[1] Valdés Cobián and his brothers, Sabino and Ramón decided to build a brewery in Mayagüez and on November 2, 1937, they founded the Compañía Cervecera de Puerto Rico which was later renamed Cervecería India.

[4] Valdés Cobián, as chairman and president, successfully led his company converting it into Puerto Rico's largest beer brewery and manufacture of canned and bottled soft drinks.

[1] Besides his chairmanship of Cervecería India, Valdés Cobián held the Orange Crush soft-drink franchise and was president of the Ana Maria Sugar Company and the Insular Feed Mill.

For 25 years he was the major stockholder and board chairman of the Banco Credito y Ahorro Ponceno,[2] which at the time was the second largest bank in Puerto Rico.

On February 8, 1988, Valdés Cobián died in San Juan, Puerto Rico, after suffering a heart attack two days earlier, at the age of 97.