At the 1900 general election he was the Liberal candidate at Manchester East, where he stood against the Conservative First Lord of the Treasury, Arthur Balfour.
In his election address he set out his political views: he supported reform of the Army, Home Rule for Ireland, the temperance movement, abolition of the House of Lords, and nationalisation or municipalisation of land, railways and mines.
Scott was defeated by the Canadian millionaire Max Aitken (later Lord Beaverbrook), who had been "parachuted" in as the Liberal Unionist candidate.
In 1913 he contested the 1913 London County Council election as a Progressive Party candidate at Greenwich but was defeated.
Scott attempted to return to the Commons, and was the unsuccessful Liberal candidate at Darlington in 1918, where the Unionist candidate was endorsed by the Coalition Government; In 1922 he stood for election to the London County Council and was defeated by a Municipal Reform Party opponent in the St Pancras South East Division.