[3] The Writers Guild of America ranked it #79 on their list of the 101 Best-Written TV Series, tying it with Monty Python's Flying Circus, Star Trek: The Next Generation and Upstairs, Downstairs.

The caricature drawing and Gounod's "Funeral March of a Marionette" have become indelibly associated with Hitchcock in popular culture.

[7][8][9] After the title sequence, Hitchcock almost always greets his audience with, "Good evening," before drolly introducing the story from an empty studio or from the set of the current episode; his usually comical monologues were written by James B. Allardice.

In the postscript, Hitchcock would briefly detail, usually unconvincingly, how fate (or the authorities) eventually brought the character to justice.

[17][18][19] The last new episode aired on June 26, 1965, but the series has continued to be popular in television syndication for decades,[20][21][9][22] including in the UK, where it is currently being shown on Sky Arts.

[23] Actors appearing in the most episodes include Patricia Hitchcock (Hitchcock's daughter), Dick York, Robert Horton, James Gleason, John Williams, Robert H. Harris, Russell Collins, Barbara Baxley, Ray Teal, Percy Helton, Phyllis Thaxter, Carmen Mathews, Mildred Dunnock, Alan Napier, Robert Vaughn and Vincent Price.

Such notables as Clint Eastwood,[24] Robert Redford, Inger Stevens, Cedric Hardwicke, Steve McQueen, Audrey Meadows, Bruce Dern, Robert Duvall, Walter Matthau, Robert Loggia, George Segal, Laurence Harvey, Claude Rains, Joan Fontaine, Thelma Ritter, Dennis Morgan, Joseph Cotten, Burt Reynolds, Vera Miles, Tom Ewell, Peter Lorre, Bette Davis, Dean Stockwell, Jessica Tandy, John Gavin, Charles Bronson, Michael Rennie, Phyllis Thaxter, Roger Moore, John Cassavetes, Peter Falk, Teresa Wright, Leslie Nielsen, Ricardo Montalbán, Harry Dean Stanton, and Barbara Bel Geddes, among many others, appeared on the series.

[42] The third season opener "The Glass Eye" (1957) won an Emmy Award for director Robert Stevens.

An episode of The Alfred Hitchcock Hour titled "An Unlocked Window" (1965) earned an Edgar Award for writer James Bridges in 1966.

[44] The episode was later referenced and remade in the film Four Rooms, with Quentin Tarantino directing a segment called "The Man from Hollywood".

The Alfred Hitchcock Presents revival series debuted in the fall of 1985 and retained the same format as the pilot: newly filmed stories (a mixture of original works and updated remakes of original series episodes) with colorized introductions by Hitchcock.

Alfred Hitchcock Presents used Charles Gounod's "Funeral March of a Marionette" (1872) as its theme song.

The ghost stories are read by actor John Allen with minimal sound effects and music.

Allen wrote four of the stories:[51] On 1 August 2024, it was announced that a stage musical adaptation of the series would have its world premiere at the Theatre Royal, Bath in March 2025, featuring music and lyrics by Steven Lutvak, book by Jay Dyer and directed by John Doyle.