In 1994 he served as Minister of Justice of the Italian Republic during the first cabinet chaired by Silvio Berlusconi.

[2] Born in Pisa, Biondi was Secretary of the Italian Liberal Party (PLI) from 1985 to 1986, and later its president.

In 1993, together with the last PLI leader, Raffaele Costa, Biondi founded the Union of the Centre, a small faction of the new Forza Italia (FI) party.

[3] Following the dissolution of Forza Italia in 2009, Biondi remained in its successor organisation, the People of Freedom (PdL), for a further two years before leaving to join the refounded Italian Liberal Party.

In 2014, Biondi was among a group of disaffected members who broke from that party to form The Liberals (I Liberali).