Ali Shayegan (Persian: علی شایگان, romanized: ʿAli Šāygān; March 1, 1903 – May 15, 1981), was an Iranian politician and an opponent of Shah Mohammad Reza Pahlavi and lived in political exile in New York and New Jersey from 1958.

Shayegan, one of the leaders of the National Front of Iran, was also a Member of Parliament, the Minister of Education and a close aide to Prime Minister Mohammed Mossadegh, whose government was overthrown by army officers loyal to the Shah in 1953 in a coup d'état orchestrated by the CIA.

Following the coup, Hossein Fatemi, also a leader in the National Front and close associate of Shayegan was executed.

While in exile, he taught at the New School of Social Research in New York City and at Fairleigh Dickinson University in Teaneck, New Jersey.

After the fall of the Shah in 1979, Shayegan returned to Iran and was mentioned as a possible candidate for the Presidency.