A number of production companies offered to buy the script for Saving Face, but Wu opted not to sell it in order to uphold an authentic portrayal of the Taiwanese-American community.

She then left the corporate world and eventually moved to New York City to pursue a filmmaking career full-time.

[4] In 2001, the script for Saving Face won the Coalition of Asian Pacifics in Entertainment screenwriting award.

It heavily focuses on the challenges faced within the Chinese-American community, dealing with issues of the role of women and lesbian identity.

[10] Although she claims that the film's main character is not an autobiographical portrayal of her real life, it was partially a way to provide positive representation for her own mother.

After Saving Face, Wu subsequently worked on a film based on Rachel DeWoskin's memoir, Foreign Babes in Beijing: Behind the Scenes of a New China.

In 2008, she sold a pitch to ABC called "Foobar" based on her experiences working as a woman in the tech world.

To get over this hurdle, Wu wrote a $1,000 check out to the National Rifle Association of America, an organization she despises, and gave it to her friend.

"[3] This draft evolved into The Half of It, a coming-of-age comedy-drama film written, directed, and produced by Wu.

[15] The film stars Charmed actress Leah Lewis, Daniel Diemer, and Alexxis Lemire in the leading roles.

"The Note" showcases one step in a young Chinese American man’s coming out journey and emphasizes the role family members can play as lifelong allies for their LGBTQ+ loved ones.

[25] In June 2020, in honor of the 50th anniversary of the first LGBTQ Pride parade, Queerty named her among the fifty heroes “leading the nation toward equality, acceptance, and dignity for all people”.