She was daughter of Thomas I of Saluzzo, and the wife of Richard Fitzalan, 1st Earl of Arundel.
Alice was born on an unknown date in Saluzzo (present-day Province of Cuneo, Piedmont); the second-eldest daughter of Thomas I, 4th Margrave of Saluzzo, and Luigia di Ceva, daughter of Giorgio, Marquis of Ceva.
Her father was a very wealthy and cultured nobleman under whose rule Saluzzo achieved a prosperity, freedom and greatness it had never known previously.
[citation needed] She was niece of Alasia of Saluzzo, who in 1247 had married an English nobleman, Edmund de Lacy, Baron of Pontefract, and was a more distant kinswoman of Eleanor of Provence, queen consort of Henry III of England.
The marriage produced: Alice died on 25 September 1292 and was buried in Haughmond Abbey, Shropshire.