Alise-Sainte-Reine (French pronunciation: [aliz sɛ̃t ʁɛn]) is a commune in the Côte-d'Or department in the Bourgogne-Franche-Comté region of eastern France.

[7][8] The theme of the oronym *alis or *ales meaning "rocky height" is the one that is currently most frequently put forward to explain the name of Alesia.

It is from an Indo-European root *palis or *pales, the initial [p] became silent in Celtic, while on the contrary it remains in Latin place names such as Palatinus (Palatine Hill) for example.

[14] In 1956 Paul Lebel did not resume this juxtaposition of the two hydronymic themes, he proposed instead for some rivers the prototype *alisa from the post-Celtic period, which is why in the case of Alesia, he ultimately opted for the oronym.

[17] The same year Ernest Nègre in his General toponymy of France, vol 1, explained the name of Alise-Sainte-Reine as pre-Celtic *alis + Gallic Suffix -ia and he indicated that it is a derivative from a designation of a spring.

[18] In 1995 the historian Francis Lassus and linguist Gerard Taverdet annotate the study by Ernest Nègre stating that his explanation by hydronym is legitimate because of the thermal spring present at Alise.

In the modern era the trade in mineral water from Alise went beyond the borders of Burgundy and even extended to Europe which lasted until the early 20th century.

[27] Alise is strongly reminiscent of Alesia and it is perhaps no coincidence since the town lies at the foot of Mont Auxois and the Gallic oppidum attested by excavations and a likely archaeological site, although still contested by some, of the ancient fortress defended by Vercingetorix.

The common symbol to represent the town is the statue of Vercingetorix erected by the orders of Napoleon III to show the strength of Gaul.

The identification of Alesia with Alise is based on a now considerable amount of archaeological and historical research: Given these facts, a consensus on the location of the battle has been reached by professional historians and archaeologists in France and abroad (where the controversy was not as great).