While the majority of the event aired live from Daily's Place in Jacksonville, Florida, the Tooth and Nail match between Dr. Britt Baker, D.M.D.

and Big Swole was pre-taped prior to the event at Baker's real-life dental clinic in Winter Park, Florida.

The event aired through traditional PPV outlets, as well as on B/R Live in North America and FITE TV internationally.

The event was originally slated to take place at the Sears Centre Arena in the Chicago suburb of Hoffman Estates, Illinois, where the previous edition of All Out was held.

This was the first AEW PPV to have ticketed fans since Revolution in February, although the capacity of the venue was reduced due to the pandemic.

The accident notably led to AEW adding new protocols in case a similar incident happens, with referees gaining the ability to use two-way communication to call medical staff and stop matches when necessary.

[4] While AEW President and Chief Executive Officer Tony Khan had stated that there would be a second All Out event, it was not officially announced until the 2020 Double or Nothing PPV in May when a second All Out show was announced as occurring during that year's Labor Day weekend on Saturday, September 5, 2020, thus establishing All Out as an annual Labor Day weekend event for AEW.

[5] Khan later stated that All Out was considered as one of AEW's "Big Four" PPVs, which includes Double or Nothing, Full Gear, and Revolution, their four biggest domestic shows produced quarterly.

On August 21, AEW began selling a limited number of tickets for events (10–15% capacity of the venue), allowing spectators to again attend shows, though with groups separated into their own pods in the upper balcony and face coverings required.

[14] Storylines were produced on AEW's weekly television program, Dynamite, the supplementary online streaming show, Dark, and The Young Bucks' YouTube series Being The Elite.

On the July 29 episode of Dynamite, #1 ranked MJF, who had never been pinned or submitted in singles competition, began a presidential election-style campaign to become the next AEW World Champion and held a "State of the Industry" address.

[16] MJF finished the speech by challenging Moxley, who also had never been pinned or submitted in singles competition, for the AEW World Championship at All Out.

The Young Bucks, in turn, removed him from The Elite, of which Page's tag partner, Kenny Omega, is still a member.

[24] On the August 27 episode of Dynamite, the Casino Battle Royale was announced to be occurring at All Out, with the winner receiving a future title match for the AEW World Championship.

During the same episode, Darby Allin, Lance Archer, Brian Cage, Ricky Starks, Penta El Zero M, Ray Fénix, The Butcher and The Blade, and Eddie Kingston were announced as the first nine participants.

On the September 2 episode of Dynamite, Austin Gunn, Billy, Jake Hager, Santana and Ortiz, Shawn Spears, and Best Friends (Chuck Taylor and Trent) were also announced for the battle royal.

[25] The second and final match on the pre-show saw Private Party (Marq Quen and Isiah Kassidy) face The Dark Order (Alex Reynolds and John Silver) (accompanied by 5 and 10).

[25] The pay-per-view opened with Britt Baker (accompanied by Rebel) facing Big Swole in a Tooth and Nail match.

[27] Next, The Dark Order (Brodie Lee, Colt Cabana, Evil Uno and Stu Grayson) (accompanied by Alan Angels) faced Scorpio Sky, Matt Cardona and The Natural Nightmares (Dustin Rhodes and Q. T. Marshall) (accompanied by Allie and Brandi Rhodes) in an eight-man tag team match.

[27] Afterwards, Kenny Omega and Adam Page defended the AEW World Tag Team Championship against FTR (Cash Wheeler and Dax Harwood).

[27] In the main event, Jon Moxley defended the AEW World Championship against MJF (accompanied by Wardlow).

Justin Barrasso of Sports Illustrated reviewed the show, saying that "tonight’s All Out show did not meet that high standard of excellence, running into a litany of obstacles that included no singles title change, a limited live crowd dealing with intense humidity and a nearly disastrous spot involving Matt Hardy".

[28] Brent Brookhouse of CBS Sports said that "while AEW All Out may have ended with a bang in the form of a competitive and entertaining world title match, the lasting memories from the show will likely be the things that did not go as planned.

[37] Similarly, during an October 18, 2022, episode of Dynamite, referee Paul Turner is seen pressing a button to call medical staff after a lariat led to "Hangman" Adam Page being injured in his match against Jon Moxley for the AEW World Championship.