[11] Opened in the fall of 2021, AHN Wexford is the network's newest full-service hospital, and includes a 24-bed emergency department, operating rooms with minimally invasive robotic surgery capabilities; a cardiac catheterization lab and hybrid OR for advanced surgical procedures; a short-stay observation unit; an adult intensive care unit; and comprehensive women's and infants' care.

The Great Depression interrupted construction, but the U.S. Public Works Administration loaned AGH the $2 million that it needed to complete the project, and on June 24, 1936, the third iteration of Allegheny General Hospital was formally dedicated.

In the decades that followed World War II, the hospital continued to expand and build, adding a new East Wing, and in 1981, a new inpatient tower, the $104 million Snyder Pavilion.

[22] In the early 1980s, AGH's directors created a nonprofit holding company, called the Allegheny Health, Education and Research Foundation, to operate the hospital.

In 1906 a committee of doctors and prominent area residents secured a charter for the establishment of what was then called the Allegheny Valley General Hospital.

[28] The three-story, brick and terra cotta structure remains standing today, at the center of what is now a much larger Allegheny Valley Hospital.

... [But], as history records, this Women's Shakespeare Club's project ended well and proved to be much ado about something pretty special: medical care.

Planning for a Monroeville hospital began in the 1960s, when two rival groups competed for the rights to build a new medical facility in eastern Allegheny County.

[20] In recent years, Forbes has continued to invest significantly in its capabilities, adding state-of-the-art robotic surgical technology, opening an inpatient rehabilitation unit, expanding and upgrading its intensive care facilities, enhancing its labor and delivery services, and establishing has the region's first and only Level II Trauma Center.

Today, the hospital is an 89-bed acute care facility in Mercer County that operates six outpatient clinics and lab sites throughout its service footprint.

After caring for an injured man, other cases were soon brought to the Sisters, until demand became so great that Mother Agnes Spencer obtained permission from Bishop Mullen to build the hospital.

After World War II came another round of expansion, and in the 1950s hospital leaders revealed plans to build a new, air-conditioned four-story inpatient center with diagnostic, X-ray, physiotherapy, lab and clinical facilities, and remodeling of business quarters.

In 2008, Saint Vincent's Neonatal Intensive Care Unit (NICU) was renovated and opened in September of that year; the new 10,000-square foot facility featured 19 individual, private pods for families to bond with their babies.

In 2017, Highmark and AHN announced $115 million in capital investments for Saint Vincent and the Erie region,[53] including a new emergency department, new operating suites, a new Women and Infants Center, and a new Health + Wellness Pavilion.

Westfield is a four-bed acute care hospital that serves several communities in New York's largely rural Chautauqua County.

In 2018, Westfield Memorial unveiled its new five-bed emergency department; the updated facility includes “four new treatment rooms and one large trauma room, along with a newly painted ambulance vestibule.”[56] In 2016, Westfield was reaccredited as an acute-care hospital by the New York Commission on Health Care Facilities in the 21st Century, the culmination of a multi-year evaluation process that reviewed the services, capacities and capabilities of all of New York's hospitals.

When the Western Pennsylvania Hospital was chartered in 1848,[59] Pittsburgh was a growing iron town, one of the largest American cities west of the Allegheny Mountains.

The first to be built were religiously affiliated, but soon, city stewards agreed that Pittsburgh would also need a publicly charted hospital that could provide health care for all, without sectarian restrictions.

[59] Because so many of the patients were indigent (most people who could afford medical care were treated by house-call doctors), the nurses and physicians who were recruited to work at West Penn did so voluntarily, in three-month rotations.

That hospital, the first specialized mental health facility in Western Pennsylvania, remained under West Penn's ownership until 1907, after which Dixmont was independently controlled.

While the fighting didn't come to Pittsburgh, wounded soldiers did, and West Penn became a primary triage center serving Union forces.

In 1883, West Penn surgeons and doctors chartered the Western Pennsylvania Medical College, which began with a class of 57 students in September 1886.

That agreement was announced in June 2011, and without the affiliation and capital infusion from Highmark, had “another investor not materialized, WPAHS was preparing a budget that would have included the autumn closure of West Penn Hospital,” according to the Pittsburgh Post-Gazette.

Today, West Penn Hospital is a 333-bed academic medical center;[20] its obstetrical program delivers nearly 4,500 babies a year, and the hospital's Level III neonatal intensive care unit, its adult and pediatric certified burn trauma center, its extended-hours oncology clinic, and dozens of other services draw patients from across the state.

[70] These large-scale pavilions were designed to provide patients and physicians with a well-organized, uniquely integrated and multi-disciplinary approach to disease management, prevention and wellness.

[76] Numerous renowned physicians, surgeons, and researchers have been affiliated with Allegheny Health Network and its member hospitals over the years, including: George J. Magovern, a pioneering cardiothoracic researcher and one of the nation's most influential heart surgeons, who developed the first suture-less heart valve, performed the world's second lung transplant in 1963, and performed one of the world's first heart transplants;[77] Peter Jannetta, who was one of the world's foremost neurosurgeons and who developed a new brain procedure to eliminate facial spasms and facial pain caused by trigeminal neuralgia;[78] Milton Jena, a distinguished cancer researcher who established one of the region's first cancer labs;[79] Donald Fisher, a cardiologist who established the region's first cardiac catheterization lab and performed one of the world's first heart defibrillations;[80] John "Jack" Gaisford,[81] a surgeon who founded Western Pennsylvania's first specialized burn center;[82] James McMaster, a leading orthopaedic surgeon and sports medicine specialist, and past president of the Allegheny-Singer Research Institute;[83] Yvonne Maher, one of the region's first female interventional cardiologists;[84] Claude Joyner Jr., whose landmark 1963 article, "Reflected Ultrasound in the Assessment of Mitral Valve Disease," introduced echocardiography to the United States;[85] and Ralph R. Mellon,[86] the director of the Institute of Pathology at West Penn Hospital through the 1930s and 1940s, and one of first doctors in the world to use sulfas (a synthetic antibiotic) to treat pneumonia and other bacterial infections.

[90] In 2020, AHN reported a $169 million operating loss, attributable to the suspension of patient visits and surgical procedures and increased supply costs necessitated by the COVID-19 pandemic.

[95] In late 2017, AHN also refinanced its debt with the issuance of $1 billion in long-term bonds,[96] purchased by a bank consortium led by PNC Financial Services.

The suit detailed actions by the two going back to 2002 that it said were designed to assure Highmark's ongoing dominance in the local insurance market while establishing higher payment rates and eliminating West Penn Allegheny to benefit UPMC.”[98] Two years after that lawsuit was filed, WPAHS's finances had further deteriorated, and WPAHS's board was contemplating a menu of options to rescue the distressed system.

But the rapid expansion came at a great cost, and soon AHERF was unable to meet debt obligations and keep up with capital improvement demands; health system leadership permitted “internal subsidies, hidden internal cash transfers and raids on hospital endowments.”[23] The rapid financial deterioration meant that by spring of 1998, AHERF was losing nearly a million dollars a day.