She was Chancellor Rishi Sunak's Director of Strategic Communications at the Treasury from April until October 2020, when she became the press secretary for 10 Downing Street.

[6][7] Stratton worked as a producer for the BBC Television current affairs programme Newsnight,[8][9] on the foreign desk at The Times, and wrote for The Independent and the New Statesman.

[11] In 2006, Stratton published a non-fiction book, Muhajababes,[12] that explored the youth culture of the Middle East and the contradictions of the modern life of young adults in Muslim societies.

[17] Private Eye magazine reported that Stratton had chosen the single mother over several other interviewees offered, including a couple with four children who had lost their jobs and faced homelessness.

[21] After a six-month hiatus, in June 2022, Stratton joined Bloomberg News as UK contributing editor, writing an afternoon newsletter called "Readout".

[25] The January launch date was repeatedly pushed back due to the COVID-19 lockdowns and on 20 April it was announced that the briefings would be scrapped entirely, with Stratton instead becoming the spokesperson for the COP26 summit that was held in Glasgow in November 2021.

[32] In the leaked 47-second clip, filmed from the Downing Street Press Briefing Room,[33] Stratton and the other staff joked about the "fictional party" being just "cheese and wine" and a "business meeting" with "no social distancing".

[37][38] Three hours later, Stratton resigned from her position as government spokesperson for the COP26 summit and apologised for her remarks which she asserted she would regret "for the rest of [her] days".