When his young band (with guitarist Joel Perry) was booked for a festival in Bedford Stuyvesant circa 1968, they turned out to be one of the opening acts for the comeback appearance of Eubie Blake.

After graduation, Lowe and his wife moved to New Haven, where he returned to his saxophone and became active in the local jazz scene with bassist Jeff Fuller and drummer Ray Kaczynski.

B., in 1985 and then recorded a series of albums with Julius Hemphill, Don Byron, David Murray, Doc Cheatham, Roswell Rudd, Loren Schoenberg, Jimmy Knepper, and Randy Sandke.

He ran the festival for three years, hiring musicians such as Tony Williams, Max Roach, Jaki Byard, Tito Puente, Freddie Hubbard, Joe Lovano, Randy Brecker, Ray Barretto, and James Moody.

Lowe lectured on musical topics and moderated panels at the Rutgers Institute of Jazz Studies[5] and the annual EMP Pop Conference in Seattle, Washington.

In 2007 he recorded Jews in Hell: Radical Jewish Acculturation with Matthew Shipp, Lewis Porter, Randy Sandke, Marc Ribot, Scott Robinson, and Erin Mckeown.