Almelo (Dutch pronunciation: [ˈɑlməloː] ⓘ) is a municipality and a city in the eastern Netherlands.

Almelo has about 72,000 inhabitants in the middle of the rolling countryside of Twente, with the industrial centres of Enschede and Hengelo as close neighbours but also with tourist towns like Ootmarsum, Delden and Markelo only a bicycle ride away.

At the end of the 19th century textile emerged as a major employer and drew many workers to Almelo, at first from within the Netherlands.

An industrial bakery, Bolletje, Malvern Panalytical, the Stichting Ziekenhuisgroep Twente (a hospital) and the regional court are also major employers.

There is also a train every 2 hours into Germany serving cities such as Osnabrück, Hannover and Berlin.