Aloïse Moudileno-Massengo was born on 11 March 1933 in the Vindza, N'Ko in the department of the Pool, the second child of a family of the Lari community.

On 20 January 1964 The Nancy Bar Association rejected his request to integrate in a decision reached by the Council of the Order because of his citizenship status.

There, on 13 January 1967, Moudileno-Massengo was named defense attorney in the Appeals Court of Brazzaville by a decree of the "Keeper of the Seals" and the Minister of Justice.

In August 1968, Moudileno-Massengo was nominated for Keeper of the Seals, Minister of Justice and of Labor, by president Alphonse Massamba-Débat.

At the age of 35, along with Ambroise Noumazalaye, Claude-Ernest Ndalla, Justin Lekoudzou and Pierre Nzé, he became part of the young intelligentsia trained in French universities and shaped politically by the anti-colonialist circles of the Association des Étudiants Congolais in France and the FEANF, whose rise within the party in power and the state apparatus contributed to the renewing of the ruling class.

His decision was criticized by his political rivals, but also by his mentor, Jacques Opangault, who feared a breakdown of the fragile North-South relationship.

In 1990, Moudileno-Massengo published a document named Call to the Nation, which was signed by the principal opposition parties both within the country and in exile.

Among the 84 other parties and political associations, he took part in the Sovereign National Conference established in February 1991 in his capacity as leader of the MPC.

In April 1992, Moudileno-Massengo was named First Deputy Director General to Elf-Congo at the demand of the Congolese State, one of the company's shareholders.

On 22 January 1993, approximately 15 political parties, including the Mouvement Patriotique Congolais, signed the founding document of the Democratic Centre.