It is a part of the Alpine Independent School District located in north-central Brewster County.

[7] Beginning in the 1960s, students were bussed to Alpine,[8] with the bus ride being the longest in the United States,[7] with 89.7 miles (144.4 km) of distance each way, totaling about one hour and 55 minutes.

Due to the distance and because there was only one bus each day, Terlingua area students could not participate in extracurricular activities after school.

[13] Residents of the Sul Ross State University family housing units, Lobo Village 5 through 7,[14] are zoned to Alpine ISD schools.

Prior to 1996, the school served, in addition to Alpine, Lajitas, Panther Junction, and Terlingua.