Alprazolam triazolobenzophenone is a chemical compound that is a prodrug for the benzodiazepine derivative alprazolam.

At neutral pH it readily cyclizes to alprazolam, while in acidic conditions alprazolam undergoes a ring-opening reaction back to the ketone.

A series of related acyl derivatives was researched in the 1980s as injectable water-soluble prodrugs of alprazolam,[1] but were never developed for medical use.

Subsequently, this compound has been detected as a designer drug, first being identified from a seizure in Spain in March 2014.

[2] This drug article relating to the nervous system is a stub.