Alpujarra Granadina is a Spanish comarca in the Province of Granada.
Along with Alpujarra Almeriense, it forms the historical region of the Alpujarras.
Located in the west of the Alpujarras, it borders the Granadan comarcas of Accitania (Guadix) to the north, the Vega de Granada to the northwest, the Valle de Lecrín to the west, and the Costa Tropical to the south, as well as the Almerían comarcas of Poniente Almeriense to the southeast and the Alpujarra Almeriense to the east.
The comarca is divided into 25 municipalities (municipios).
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