Altagène (French pronunciation: [altaʒɛn]; Corsican: Altaghjè pronounced [al.ta.ˈɟe]) is a commune in the Corse-du-Sud department in the Corsica region of France.

Access to the commune is by road D49 running north from Sainte-Lucie-de-Tallano and ending in the village.

The D320 also runs north from Sainte-Lucie-de-Tallano through the western part of the commune and continues to Zoza as road D20.

There are some small mountain roads through the commune which is steeply sloped and heavily forested.

The commune has a number of buildings and structures that are registered as historical monuments: The Parish Church of Saint Pantaléon (19th century) is registered as an historical monument.