The River Dragons play in the Prospect League's Western Conference – South Division along with the Cape Catfish, Jackson Rockabillys, O'Fallon Hoots, and Thrillville Thrillbillies.

[1] On January 29, 2020, the Prospect League of collegiate summer baseball announced that Alton, Illinois had been granted a franchise for the upcoming season.

The River Dragon's Eddie King Jr. from the University of Louisville was named the Mike Schmidt Prospect League Player of the Year.

On October 5, 2022, the River Dragons announced the hiring of Richard "Scotty" Scott as the team's next Head Coach.

After going 15-29 Head Coach Scotty Scott was replaced by River Dragons General Manager Dallas Martz to finish out the 2023 season.