The road was designed for a speed of 120 mph with straight alignments, avoiding habitations and locations of archaeological and religious importance.

Tunnels and viaducts were proposed to be constructed to avoid hilly terrains and valley sections.

The spinal corridor takes off from NH-44 near Maruru in Ananthapuramu District and ends at Pedaparimi near Sakhamuru, thereby crossing the Vijayawada IRR near Tadikonda and ORR near Velavarthipadu.

6-lane road starts from Yadavalli which forms a single straight stretch to the state capital.

The expressway is proposed to be designed as a high-speed corridor by making it completely access-controlled.

[14] Anantapur, Tadipatri, Kolimigundla, Belum Caves, Owk, Banaganapalli, Nandyal, Gajualapalli, Giddalur, Cumbum, Thokapalli, Vinukonda, Narasaraopet, Guntur.