Amastatin, also known as 3-amino-2-hydroxy-5-methylhexanoyl-L-valyl-L-valyl-L-aspartic acid, is a naturally occurring, competitive and reversible aminopeptidase inhibitor that was isolated from Streptomyces sp.

[5][6] Amastatin has been found to potentiate the central nervous system effects of oxytocin and vasopressin in vivo.

[7] It also inhibits the degradation of met-enkephalin, dynorphin A, and other endogenous peptides.

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