[9] At the beginning of the 1st century BC, Amathus was an important fortress held by Theodorus, son of the tyrant Zeno Kotoulas of Philadelphia.
[13][15][16] Amathus was part of the Herodian kingdom and then of Judaea Province of the Roman Empire from 44 AD.
In about 390, it became part of the newly created province of Palaestina Prima, whose capital was Caesarea Maritima.
In 518, Procopius signed the letter of the bishops of Palestine to Patriarch John II of Constantinople against Severus of Antioch.
[17][18] No longer a residential bishopric, Amathus in Palaestina is today listed by the Catholic Church as a titular see.