America's Most Musical Family is an American reality music competition television program that aired on Nickelodeon from November 1, 2019 to January 17, 2020.

The Melisizwe Brothers were announced as the winning band of the series.

On February 14, 2019, it was announced that Nickelodeon was developing a reality competition television series under the working title of America's Most Musical Family.

[1][2] On July 25, 2019, Nick Lachey was announced as the host of the program, while Ciara, David Dobrik, and Debbie Gibson as judges on the program.

Production on the program began in Los Angeles in July 2019.