Founded in 2002, the AISL's headquarters were in West Springfield, Massachusetts, but the media relations office was in Cleveland, Ohio.

The 2005–06 season started with promise, starting with six teams, but the New Mexico Storm and Detroit-Windsor Border Stars decided not to play in the AISL just before the season got under way.

In 2006, the league announced the membership of the Canton Crusaders,[1] but the team's membership was revoked after the ownership was unable to fulfill its financial obligations.

In 2008 with the Cincinnati Excite going on hiatus, and the Massachusetts Twisters and Rockford Rampage moving to the National Indoor Soccer League, the 2008–09 campaign was canceled.

On December 23, 2008, all news stories were dropped from the website.