The film's ensemble cast features many actors who reprise their roles from the previous three films, including Jason Biggs, Alyson Hannigan, Chris Klein, Thomas Ian Nicholas, Seann William Scott, Eddie Kaye Thomas, Eugene Levy, Tara Reid, and Mena Suvari, among others.

The film follows former East Great Falls High School classmates who return to their hometown for a reunion for their graduating class.

Kevin Myers is a househusband and architect, Chris "Oz" Ostreicher is a celebrity sportscaster dating Mia, a superficial supermodel, and Paul Finch has been traveling the world.

Seeking revenge, the boys trace AJ and his friends to a beach where Jim overhears his plans to take the virginity of Kara—Jim's neighbor whom he used to babysit—now she has turned 18.

Instead of spending time with Michelle, Jim accompanies the others to the Falls to reminisce about high school, where they come across teens partying for Kara's birthday.

She passes out and Jim recruits Stifler, Finch, and Oz to distract her parents while he sneaks her into their house, worried Michelle will think he cheated on her.

Kevin reconciles with Vicky and introduces her to his wife, Finch makes amends for lying to Selena, and Oz and Heather choose to be together.

The boys meet up the following day: Oz reveals he is staying in town with Heather; Finch intends to tour Europe with Selena; and Jim apologizes to Kara, who plans to save her virginity for a good man like him.

[5] In April 2010, the film entered pre-production, with Jon Hurwitz and Hayden Schlossberg signing on to write and direct with plans to reunite the whole cast of the primary series.

National Football League wide receiver Chad Ochocinco and actor Neil Patrick Harris have cameo roles.

Scenes were filmed at the school's gym for a reunion prom set, football field, commons area and hallways; which included 200 extras.

[23] During the last week of July, production moved to Cumming to film at Mary Alice Park on Lake Lanier and included about 100 extras.

[citation needed] American Reunion opened in North America on April 6, 2012 in 3,192 theaters for a weekend total of $21,514,080, putting it at number 2 at the box office behind The Hunger Games.

The site's critical consensus reads, "It'll provide sweetly nostalgic comfort food for fans of the franchise, but American Reunion fails to do anything truly new or interesting – or even very funny – with the characters.

[32] According to Roger Ebert, who gave the film three out of four stars:[33] The charm of American Pie was the relative youth and naïveté of the characters.

Otherwise, I dunno.The Village Voice concludes its review with the following:[34] After some strained "Remember the time..." callbacks to 13-year-old gags, American Reunion gets comfortable and funny, as Hurwitz and Schlossberg hit familiar marks from unexpected angles, while the ensemble interplay is "routine" in the best sense of the word.

Taken altogether, the Pie movies offer a cohesive worldview, showing each of life's stages as the setting for fresh-yet-familiar catastrophes, relieved by a belief in sex, however ridiculous it might look, as a restorative force.

The recipe is so durable and the sustained character work so second-skin by now, one can imagine the Pie films keeping with the dramatis personae through middle age and into the problems of geriatric love, a raunch-comic version of Britain's documentary Up series.