On 6 September 2008, Khan suffered an upset first round knockout defeat against undefeated contender Breidis Prescott.

Scoring a second-round TKO over Brian Carden in March, and a PTS victory over Konstantins Sakara in July.

[4][5] On 30 October 2008, it was announced that Khan and Fagan would fight on 6 December 2008 at the ExCel in London, on the undercard of Nicky Cook's defence of his WBO super-featherweight title.

[6] It was later announced that Khan and Fagan would headline the event, live on Sky Sports Box Office, along with Oscar De La Hoya vs. Manny Pacquiao.

[7] From the opening bell, Khan started fast, using his jab, with Fagan attempting to close the distance and apply pressure.