He wrote several works on medicine and science, some aimed at professional audiences and some at ordinary people.

All his works were written in Middle Armenian, making them accessible to ordinary readers and not just to scholars.

Wandered as a travelling physician in Asia and Iran collecting plant samples End of 1450s: Moved to Constantinople by sea.

1470s: Returned to Constantinople, regained his position of a chief physician to Mehmed II, enjoying his confidence until the ruler's death in 1481.

1480s: Returned to his motherland upon the invitation of the son of Mehmed II, Ahmed, who became a ruler of Amasia.