The Amos B. Coe House is a historic home in Minneapolis, Minnesota, United States.

It was built for a local real estate developer in 1884 in the Eastlake Style of Queen Anne architecture.

[1] Attorneys for the construction, plumbing and electrical companies that had previously won a court judgment for unpaid work at the museum joined to purchase the property for $1.3 million: the total amount a judge found that they are owed.

Beginning in 2008, the Minnesota African American Museum and Cultural Center occupied the structure.

Although the museum spent several million dollars on improvements, its fundraising effort failed to cover the cost of renovations.