After her shortened reign, Muñoz became a popular actress in Spain and starred in several comedies, including Mama Turns 100, and in the dramas Clara es el Precio, The Other Bedroom and Dedicatory.

She died on 27 February 2011 due to cerebral aneurysm complications and was cremated and buried at the Roman Catholic cemetery of Saint Michael in Málaga, Spain.

Born in the Marian year of 1954, she was named after the Blessed Virgin Mary under the title of “Our Lady of the Abandoned” (Spanish: Nuestra Señora de los Desamparados) the firstborn child among six children.

Amparo Muñoz came from the town of Vélez-Málaga (Málaga) in Andalusia, where she had won the city title, to compete at the Miss Spain contest held in Lanzarote.

In the 70’s, Spanish cinema was at the height of destape [double meaning: "liberalization" and "nudity"], and the splendid figure of Amparo Muñoz found 9 titles in which to reveal itself, including Clara es el Precio (Vicente Aranda, 1975), and The Other Bedroom (Eloy de la Iglesia, 1976), in which Amparo starred alongside the man who would be eventually her husband, the actor and singer Patxi Andión.

After appearances in Volvoreta (José Antonio Nieves Conde, 1976), Del Amor y de la Muerte (Antonio Giménez Rico, 1977), among other films, her cinematic career took a notable turn when she began a relationship with the producer Elías Querejeta, facilitating her appearances in films as important as Dedicatory (Jaime Chávarri, 1980), which called her to the attention of other directors in both Spain and Mexico, such as Felipe Cazals (Las siete cucas ), Pilar Miró (We Will Speak Tonight), Jaime Camino (The Open Balcony), Emilio Martínez Lázaro (Lulú of the Night), Imanol Uribe (The Black Moon).

In 1991, she lived with Victor Guijarro in the Philippines, thereby disappearing from film for seven years (1989—1996), but eventually her immediate family requested her return to Spain, during which began the alleged melancholia and extreme mental depression of Muñoz.

Accordingly, though raised and baptized Roman Catholic, Muñoz later dabbled and experimented with various New Age philosophies, including “Mikyo Dorje Karmapa” in Tibetan Buddhism, Indonesian—Balinese Hinduism and Soka Gakkai practices during the early 1990s.

Returning to Spain in 1996, growing tabloid newspaper accusations of prostitution, mental depression, heroin drug addiction, Parkinson's disease, and Human Immunodeficiency Virus coupled with poverty and melancholia ravaged Muñoz' public image, along with the physical decrepitude allegedly causing emotional shame and her imminent withdrawal from society.

Later on, she dated both Flavio Labarca when she lived in Mexico in 1980 and Víctor Rubio Guijarro in the Philippines in 1991, both who suffered from drug abuse by which Muñoz called off in both relationships.

Muñoz was duly advised by her physicians of imminent death in which she suffered two more cerebral aneurysms, the first case which paralyzed half of her body, the latter which partially impaired her vision.