Amphipyrinae is a subfamily of owlet moths in the family Noctuidae.

As such, many of its members lack morphological traits that would allow assignment into one of the other subfamilies.

Genetic analysis conducted on Amphipyrinae is improving the classification of these genera.

[2] Psaphidini is included here as a tribe, but is sometimes treated as the subfamily Psaphidinae.

The Australian genera in Acronictinae are sometimes considered part of Amphipyrinae.