[1][4] During the 1980s and 90s, Amref expanded in scope, collaborating with other international aid agencies and working directly with the Ministries of Health in Tanzania, Kenya and Uganda on community health based projects, with a focus on the prevention of HIV/AIDS.

[4] In the 2000s and 2010s, Amref performed thousands of reconstructive surgeries on Africans with cleft lip and cleft palate (CLP) alongside the non-profit organization Smile Train.

[1] In 1969, Amref was the subject of a documentary short by director Werner Herzog named "The Flying Doctors of East Africa.

According to Herzog, the film was successful in bringing publicity to the organization in its early days.

Daktari: A Surgeons Adventures with the Flying Doctors of East Africa.