The daughter of a minister, Black spent her early years in Missouri and Alabama before relocating with her family to Boston, Massachusetts.

She formed the band Amy Black and the Red Clay Rascals, an acoustic roots music ensemble, and began to play at Boston area venues.

[16] In January 2017, Black recorded an album of original soul music and several classics in Memphis, Tennessee with grammy-nominated producer, Scott Bomar (also the leader of the Memphis-based band, The Bo-Keys.)

Black has opened shows for artists including The Mavericks, Delbert McClinton, Patti Griffin, Chris Isaak, James McMurtry, The Court Yard Hounds, Rodney Crowell, Suzy Bogguss, Joe Ely, Eilen Jewell,[19] Lori McKenna, Emmylou Harris,[20] John Hammond, Charlie Musselwhite, and Kelly Willis.

Boston Herald music critic Nate Dow wrote, “it is the beautifully imagined sound and soul of her originals that make her a newcomer of note.”[22] Country news site Roughstock noted "Amy Black is something uncommon in the contemporary era.

"[23] Americana and roots music magazine No Depression observed of her live performances, "Black has a rich voice layered with a light, natural vibrato.

She slays you by being sly...This Is Home is an effortless blend of roots, country, and blues – with a touch of R&B-and further establishes Black's songwriting abilities.

"[30] Blues in Britain magazine also praised Black's "deeply soulful voice that melds elements of Dusty Springfield, Mavis Staples, and Alberta Hunter.

Released on her own label Reuben Records, the aptly titled album shines a light on Black's love for the iconic city that has been home to some of the greatest blues, soul, country and rock 'n' roll ever produced.