Amy Denio (born June 9, 1961) is a Seattle-based multi-instrumental composer of soundtracks for modern dance, film and theater, as well as a songwriter and music improviser.

She has performed and recorded with (among others) Matt Cameron, KMFDM, Curlew, Fred Frith, Pointless Orchestra, Francisco López, Danny Barnes, Pale Nudes, Blowhole, the Danubians, The Science Group, Chris Cutler, Guy Klucevsek, Pauline Oliveros, Relâche Ensemble, Hoppy Kamiyama, Derek Bailey, Chuck D, Dennis Rea, Bill Rieflin, Quintetto alla busara, Kultur Shock, and the Shaking Ray Levis.

She was sponsored by Jazz India to live in Bombay and study Thumri, Northern Indian vocal technique from Dhanashree Pandit-Rai in 1997.

Since 1988, she has performed at festivals in India, Japan, Hong Kong, Taiwan, Brazil, Argentina, North America, and throughout East and Western Europe.

In 2007, she was commissioned by the Dream Community in Taipei, Taiwan to arrange, record and produce Taiwanese aboriginal and popular music with samba rhythms from Brazil.