She performs solo and as half the duo The Delightful Sausage with Chris Cantrill.
[4] Between 2020 and 2021, Gledhill appeared as various characters in the CBBC and BBC iPlayer children's sketch show Big Fat Like.
[9] In 2023 Gledhill embarked on her first solo UK tour after a sold-out run at the Soho Theatre in London.
Happy Valley alongside fellow comedian Isy Suttie, in which they "discuss fan theories and chat to familiar faces from the cast".
[17] In October 2024, Gledhill and fellow comedian Harriet Kemsley launched a podcast called Single Ladies In Your Area, where they discuss, with guests, modern dating after the break-up of their respective long-term relationships.