She released her debut album Así Soy Yo (translated as "This Is The Way I Am") on April 18, 2006, where it peaked as number 79 on the Billboard Hot 100.

The album was preceded by the singles "Atrapada", "Lo Que Son Las Cosas", "Estoy Con Él Y Pienso En Ti", and "Estar Contigo".

"Lo Que Son Las Cosas", which was originally made famous by Ednita Nazario, charted and peaked at number 79 on the Billboard Hot 100 and topped the Hot Latin Tracks chart for 6 weeks straight, earning her four Billboard Award nominations.

During this time, Anaís performed the song "Como Tu Mujer" in a televised tribute to Mexican singer Marco Antonio Solís.

Solís was so impressed by the performance that he invited Anaís as a special guest and opening act for his concert in Madison Square Garden.

[9] Anaís parted ways with Univision, instead becoming an independent artist while attempting kickstart her music career in the United States.

[10] She released several independent pop singles during this period, including "Own It" on May 23, 2012,[11] "Naked" on October 4, 2016,[12] "Hostage" on March 24, 2017[13] and "Too Young" on August 11, 2017.