Since then, she has starred in various soap operas such as Al norte del Corazón, Señora, Amor Latino and Romántica obsesión, for which she won the Sol de Oro award in 1999 for Best New Actress.

Talancón's big-screen acting debut was with the film El Cometa by Marisa Sistach, playing the character Valentina, for which she was nominated for the Ariel award for Best New Actress.

In 2006, Talancón appeared in Richard Linklater's Fast Food Nation as Coco, a Mexican immigrant forced to work in a meatpacking plant.

[1] She appeared in other movies such as The Virgin of Juarez, in which she received the award for the Best Supporting Actress at the BendFilm Festival and Mujer Alabastrina'’.

One year later in 2008, she starred in One Missed Call, which was nominated at the Teen Choice Awards, Tear This Heart Out (Arráncame la Vida) and Days of Wrath, plus a Mexican TV series, Terminales.